Effects of psoralen on hepatic bile acid transporters in rats
Abstract
Fructus Psoraleae (FP), widely used in traditional medicine, is increasingly reported to cause serious hepatotoxicity in recent years. However, the main toxic constituents responsible for hepatotoxicity and the underlying mechanisms are poorly understood. In the present study, psoralen, a main and quality-control constituent of FP, was intragastrically administered to Sprague-Dawley rats at a dose of 60 mg/kg for 1, 3 and 7 days. Blood and...
Paper Details
Title
Effects of psoralen on hepatic bile acid transporters in rats
Published Date
Dec 15, 2020
Volume
40
Issue
6
Pages
1012 - 1021
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