Decreased complexity and increased variability in systolic blood pressure are associated with elevated long‐term risk of dementia: The Rotterdam Study

Background Blood pressure (BP) is a key player in the vascular etiology of dementia, but their relationship is not fully elucidated. The current BP control paradigm focuses on BP levels, but real‐time BP is highly dynamic, involving simultaneous interactions of numerous neural and vascular feedback mechanisms. We hypothesized that early subclinical disruption in BP dynamics, captured by decreased complexity and increased variability, contributes...