Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
Abstract
Background In the last years, several clinical trials have proved the safety and efficacy of adipose-derived stem/stromal cells (ASC) in contrasting osteoarthritis (OA). Since ASC act mainly through paracrine mechanisms, their secretome (conditioned medium, CM) represents a promising therapeutic alternative. ASC-CM is a complex cocktail of proteins, nucleic acids, and lipids released as soluble factors and/or conveyed into extracellular vesicles...
Paper Details
Title
Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
Published Date
Dec 1, 2020
Journal
Volume
11
Issue
1
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