Antibacterial application and toxicity of metal-organic frameworks.

Published on Mar 16, 2021in Nanotoxicology4.925
· DOI :10.1080/17435390.2020.1851420
Wanling Zhao1
Estimated H-index: 1
(Guangzhou University of Chinese Medicine),
Jinqiong Deng1
Estimated H-index: 1
(Guangzhou University of Chinese Medicine)
+ 5 AuthorsSijun Liu1
Estimated H-index: 1
(Guangzhou University of Chinese Medicine)
Sources
Abstract
Metal–organic frameworks (MOFs), which are also referred to as coordination polymers, have been widely used in adsorption separation and catalysis, especially in the field of physical chemistry in ...
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#1Zihao Wang (Cornell University)H-Index: 1
#2Zongzhe Li (Cornell University)H-Index: 1
Last. Phillip J. Milner (Cornell University)H-Index: 18
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Metal–organic frameworks (MOFs) bearing coordinatively unsaturated metal centers, exemplified by the MOF-74 family of frameworks, are promising for applications ranging from gas separations and storage to Lewis acid catalysis. However, the scalable synthesis of MOF-74 analogues remains a significant challenge. Recently, mechanochemistry has emerged as a sustainable strategy for the preparation of MOFs in the solid state with minimal solvent waste. Mechanochemical methods typically rely on metal ...
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#2Jenjira Phuriragpitikhon (Liquid Crystal Institute)H-Index: 4
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Abstract Graphene oxide-containing ordered mesoporous carbon (OMC/GO) composites were synthesized by mechanochemical soft-templating of mimosa tannin and graphene oxide with triblock copolymer Pluronic F127. Graphene oxide was added to modify the surface properties of ordered mesoporous carbon. Next, copper containing MOF (CuBTC) was synthesized in the presence of the OMC/GO composite via dry milling to obtain a three-component composites with different compositions. The composite with 50 wt % o...
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#1Siyu Wang (JLU: Jilin University)H-Index: 1
#2Fei Yan (JLU: Jilin University)H-Index: 1
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Abstract Developing wound dressing that inhibits bacterial infection for treating complex wound healing processes has been a research hotspot. Here, we report the fabrication of Cu-MOFs (HKUST-1) incorporated electrospun chitosan/polyvinyl alcohol (HKUST-1/chitosan/PVA) fibers through the blending electrospinning for wound therapy. HKUST-1/chitosan/PVA fibers displayed satisfying physical properties, such as mechanical property, water uptake, water vapor transmission rate, etc. Cytotoxicity test...
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#1Xiqing Cheng (Ha Tai: Xiamen University)H-Index: 4
#2Shuai Zhang (Ha Tai: Xiamen University)H-Index: 2
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Encapsulating nanopartiles/biomolecules into metal-organic freamworks (MOFs) has proven highly effective in creating new functions during their applications. However, it is highly desirable yet remains challenging to achieve the synergy of specific functions between MOF host and guest species. Herein, inspired by natural multienzyme system, a novel MOF composite biomimetic structure based on co-encapsulation of glucose oxidase (GOx) and L-arginine (L-Arg) into Cu-MOFs (CuBDC) with Fenton-like ca...
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Abstract HKUST-1, a Cu-based metalorganic framework (MOF), was synthesized solvothermally, functionalized with polyethyleneimine (PEI), and hybridized with graphene oxide (GO) and functionalized GO for H2S removal. MOF synthesis approach, molecular weight of amines, and the content of GO in the hybrid adsorbents were systematically varied. The adsorbent materials were characterized by XRD, FTIR, SEM, elemental analysis, liquid N2 adsorption-desorption, water vapor and oxygen sorption, and subseq...
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#1Yi Cao (CAS: Chinese Academy of Sciences)H-Index: 16
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Zeolitic imidazolate frameworks (ZIFs) as emerging porous materials have attracted remarkable attention for their unprecedented porosity and acidic sensitive degradation that enables high drug loading and microenvironment responsive fast payload release. However, the limited functions and disadvantages of ZIFs such as early drug release, potential cytotoxicity inducing damage to major organs, and even death of animals, impede their further biomedical application. In this work, we report the firs...
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#2Yanqing Xia (Zhengzhou University)H-Index: 3
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Background: Metal-organic frameworks (MOFs) have attracted intensive research interest in the biomedical field because of their unique properties. However, in order to realize the high loading capacity and therapeutic efficacy, it is still urgent to develop a multifunctional MOFs-based nanoplatform. Materials and Methods: Herein, a pH/near-infrared (NIR) dual-responsive drug delivery system based on zeolitic imidazolate framework-8 (ZIF-8) is constructed for synergistic chemo-photothermal therap...
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Metal-organic frameworks (MOFs), have high porosity and surface area, making them ideal candidates for adsorption-mediated applications. One high value application is the removal of uremic toxins from solution for dialysis. Previous studies have reported adsorptive removal of the uremic toxin p-cresyl sulfate from solution via zirconium-based MOFs, but a specific analysis of parameters contributing to adsorptive uptake is needed to clarify differences in uptake performance be-tween MOFs. We synt...
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Therapeutic enzymes used for genetic disorders or metabolic diseases oftentimes suffer from suboptimal pharmacokinetics and stability. Nanodelivery systems have shown considerable promise for impro...
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Iron(III) aminoterephthalate Metal-Organic Frameworks (Fe-BDC-NH2 MOFs) have been demonstrated to show potential for relevant industrial and societal applications (i.e., catalysis, drug delivery, gas sorption). Nevertheless, further analysis is required in order to achieve their commercial production. In this work, a systematic synthetic strategy has been followed, carrying out microwave (MW) assisted hydro/solvothermal reactions to rapidly evaluate the influence of different reaction parameters...
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Abstract Diseases caused by microorganisms have significantly impacted public health. Metal–organic frameworks (MOFs) and MOF-based materials with unique physical and chemical properties have shown promise as candidates for potent antimicrobial agents. In this review, the structural characteristics of MOFs that are demonstrated to be the main structural determinants in microorganism inactivation are discussed, with a particular focus on the type(s) of metal clusters, organic ligands, nanoparticl...
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