Modulation of dendritic spines by protein phosphatase-1

Pages: 117 - 144
Published: Jan 1, 2021
Abstract
Protein phosphatase-1 (PP-1), a highly conserved multifunctional serine/threonine phosphatase, is enriched in dendritic spines where it plays a major role in modulating excitatory synaptic activity. In addition to established functions in spine maturation and development, multi-subunit holoenzyme forms of PP-1 modulate higher-order cognitive functions such learning and memory. Mechanisms involved in regulating PP-1 activity and localization in...
Paper Details
Title
Modulation of dendritic spines by protein phosphatase-1
Published Date
Jan 1, 2021
Pages
117 - 144
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