Renal Phosphate Handling: Independent Effects of Circulating FGF23 , PTH , and Calcium
Abstract
Excess fibroblast growth factor 23 (FGF23), excess PTH, and an increase in extracellular calcium cause hypophosphatemia by lowering the maximum renal phosphate reabsorption threshold (TmP/GFR). We recently reported two cases of X-linked hypophosphatemia (XLH) with severe tertiary hyperparathyroidism who had normalization of TmP/GFR upon being rendered hypoparathyroid following total parathyroidectomy, despite marked excess in both C-terminal...
Paper Details
Title
Renal Phosphate Handling: Independent Effects of Circulating FGF23 , PTH , and Calcium
Published Date
Dec 9, 2020
Journal
Volume
5
Issue
2
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