CheckMate 743: A Glimmer of Hope for Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is a rare, locally invasive, and highly aggressive cancer originating from the serosal surface of the pleura. Radical surgery, as a part of multimodality treatment, is recommended for early-stage disease with epithelioid histology. However, a significant number of patients have advanced disease at presentation, and front-line chemotherapy in the form of platinum-pemetrexed is the current standard of care....