ET-06 Suppression of glioblastoma through novel drug based on “Gene Switch Technology”
Abstract
Glioblastoma (GBM) is the most common and aggressive malignancy primarily affecting adults. Despite intensive multimodal therapies, the prognosis of GBM is dismal and a novel therapy is needed. Here, we focused on RUNX, a transcription factor involved in the malignant transformation of GBM, and developed a novel Chlorambucil-conjugated PI-polyamides (Chb-M’), which “switches off” RUNX family. Chb-M’ specifically recognizes the consensus...
Paper Details
Title
ET-06 Suppression of glioblastoma through novel drug based on “Gene Switch Technology”
Published Date
Nov 1, 2020
Journal
Volume
2
Issue
Supplement_3
Pages
ii6 - ii6
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Notes
History