Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues

Volume: 15, Issue: 11, Pages: e0242599 - e0242599
Published: Nov 23, 2020
Abstract
Sensorineural hearing loss is one of the most common disabilities worldwide. Such prevalence necessitates effective tools for studying the molecular workings of cochlear cells. One prominent and effective vector for expressing genes of interest in research models is adeno-associated virus (AAV). However, AAV efficacy in transducing cochlear cells can vary for a number of reasons including serotype, species, and methodology, and oftentimes...
Paper Details
Title
Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues
Published Date
Nov 23, 2020
Journal
Volume
15
Issue
11
Pages
e0242599 - e0242599
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