Tackling solid tumour therapy with small-format drug conjugates
Abstract
The pharmacokinetic–pharmacodynamic relationship is extremely complex and tumour drug penetration is one key parameter influencing therapeutic efficacy. In the context of antibody–drug conjugates (ADCs), which has undergone many innovation cycles and witnessed many failures, this feature is being addressed by a number of alternative technologies. Immunoglobulin-based ADCs continue to dominate the industrial landscape, but smaller formats offer...
Paper Details
Title
Tackling solid tumour therapy with small-format drug conjugates
Published Date
Nov 25, 2020
Journal
Volume
3
Issue
4
Pages
237 - 245
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Notes
History