Defective HLA Class I Expression and Patterns of Lymphocyte Infiltration in Chordoma Tumors

Volume: 479, Issue: 6, Pages: 1373 - 1382
Published: Jun 1, 2021
Abstract
Background There are no effective systemic therapies for chordoma. The recent successes of immunotherapeutic strategies in other cancers have resulted in a resurgence of interest in using immunotherapy in chordoma. These approaches rely on a functional interaction between the host’s immune system and the expression of tumor peptides via the human leukocyte antigen (HLA) Class I antigen. It is not known whether chordoma cells express the HLA...
Paper Details
Title
Defective HLA Class I Expression and Patterns of Lymphocyte Infiltration in Chordoma Tumors
Published Date
Jun 1, 2021
Journal
Volume
479
Issue
6
Pages
1373 - 1382
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