Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells

Volume: 7
Published: Dec 1, 2020
Abstract
Background: Endothelial function significantly depends on the proteolytic release of surface expressed signal molecules, their receptors and adhesion molecules via the metalloproteinase ADAM17. The pseudoproteases iRhom1 and 2 independently function as adapter proteins for ADAM17 and are essential for the maturation, trafficking, and activity regulation of ADAM17. Bioinformatic data confirmed that immune cells predominantly express iRhom2 while...
Paper Details
Title
Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells
Published Date
Dec 1, 2020
Volume
7
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.