Suntamide A, a neuroprotective cyclic peptide from Cicadidae Periostracum
Abstract
Suntamide A (1), a new cyclic peptide, was isolated from Cicadidae Periostracum. The gross structure of 1 was elucidated by detailed analysis of HRMS and 1D/2D NMR spectra, and the absolute configuration was established by C3 Marfey’s method. We extended our study to examine biological activity of 1, and found that 1 protected SH-SY5Y cells against rotenone-induced neurotoxicity. This effect of 1 seemed to be attributed to antioxidant induction...
Paper Details
Title
Suntamide A, a neuroprotective cyclic peptide from Cicadidae Periostracum
Published Date
Jan 1, 2021
Journal
Volume
106
Pages
104493 - 104493
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