Hypoxia-induced miR-210 modulates inflammatory response and fibrosis upon acute peripheral ischemia
Abstract
Introduction We previously demonstrated in mouse models of peripheral and heart ischemia that miR-210 is necessary and sufficient to stimulate blood perfusion recovery, as well as arteriolar and capillary density increase following ischemic damage. Aim To clarify the role of inflammatory cells in miR-210-induced angiogenesis. Methods and results In a mouse model of acute limb ischemia, miR-210 loss-of-function was obtained by administration of...
Paper Details
Title
Hypoxia-induced miR-210 modulates inflammatory response and fibrosis upon acute peripheral ischemia
Published Date
Nov 1, 2020
Journal
Volume
41
Issue
Supplement_2
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History