Angel or Devil ? - CDK8 as the new drug target
Abstract
Cyclin-dependent kinase 8 (CDK8) plays an momentous role in transcription regulation by forming kinase module or transcription factor phosphorylation. A large number of evidences have identified CDK8 as an important factor in cancer occurrence and development. In addition, CDK8 also participates in the regulation of cancer cell stress response to radiotherapy and chemotherapy, assists tumor cell invasion, metastasis, and drug resistance....
Paper Details
Title
Angel or Devil ? - CDK8 as the new drug target
Published Date
Mar 1, 2021
Volume
213
Pages
113043 - 113043
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