Bispecific monoclonal antibodies for targeted immunotherapy of solid tumors: Recent advances and clinical trials

Volume: 167, Pages: 1030 - 1047
Published: Jan 1, 2021
Abstract
Bispecific antibodie (BsAbs) combine two or more epitope-recognizing sequences into a single protein molecule. The first therapeutic applications of BsAbs were focused on cancer therapy. However, these antibodies have grown to cover a wider disease spectrum, including imaging, diagnosis, prophylaxis, and therapy of inflammatory and autoimmune diseases. BsAbs can be categorized into IgG-like formats and non-IgG-like formats. Different...
Paper Details
Title
Bispecific monoclonal antibodies for targeted immunotherapy of solid tumors: Recent advances and clinical trials
Published Date
Jan 1, 2021
Volume
167
Pages
1030 - 1047
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