Pyridoxine for prevention of hand–foot syndrome caused by chemotherapy agents: a meta‐analysis

Hand–foot syndrome (HFS) is a common systemic skin toxicity syndrome caused by chemotherapy agents. However, there is no uniform clinical treatment for HFS. It is reported that pyridoxine (vitamin B6) can be used to prevent HFS, but the evidence is insufficient. To determine whether pyridoxine can be used to prevent HFS caused by chemotherapy agents. Literature database searches were performed on PubMed, Web of Science, Embase, Cochrane Library...