Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells
Abstract
Neutrophils are the first cells recruited at the site of infections, where they phagocytose the pathogens. Inside the phagosome, pathogens are killed by proteolytic enzymes that are delivered to the phagosome following granule fusion, and by reactive oxygen species (ROS) produced by the NADPH oxidase. The NADPH oxidase complex comprises membrane proteins (NOX2 and p22 phox ), cytoplasmic subunits (p67 phox , p47 phox , and p40 phox ) and the...
Paper Details
Title
Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells
Published Date
Nov 12, 2020
Volume
8
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