Thrombosis and thromboprophylactic strategies in the adult with Fontan circulation

The Fontan procedure has evolved into the treatment of choice for infants with single ventricle physiology. The procedure and its modifications have extended survival of such patients into adulthood. However, adult patients face late complications, of which thromboembolic events (TEE) are considered complex and challenging in pathophysiology and management. All three components of Virchow's triad are affected in Fontan circulation. Remarkably,...