Long-term effects of intensive B cell depletion therapy in severe cases of IgG4-related disease with renal involvement
Abstract
IgG4-related disease (IgG4-RD) is an immune-mediated disorder often showing elevated serum IgG4 concentrations, dense T and B lymphocyte infiltration, and IgG4-positive plasma cells and storiform fibrosis. We prospectively evaluated for 4 years 5 patients with histologically proven IgG4-RD of whom 3 had tubulointerstitial nephritis (TIN) and 2 had retroperitoneal fibrosis (RPF). They received an intensive B depletion therapy with rituximab. The...
Paper Details
Title
Long-term effects of intensive B cell depletion therapy in severe cases of IgG4-related disease with renal involvement
Published Date
Nov 10, 2020
Journal
Volume
68
Issue
6
Pages
340 - 352
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History