The role of phytochemicals in sepsis: A mechanistic and therapeutic perspective

Volume: 47, Issue: 1, Pages: 19 - 40
Published: Nov 20, 2020
Abstract
Sepsis and septic shock are still a leading cause of mortality and morbidity in intensive care units worldwide. Sepsis is an uncontrolled and excessive response of the innate immune system toward the invading infectious microbes, characterized by the hyper-production of pro-inflammatory mediators such as interleukin (IL)-1β, IL-6, tumor-necrosis factor (TNF)-α, and high-mobility group box 1 (HMGB1). In severe sepsis, the overwhelming production...
Paper Details
Title
The role of phytochemicals in sepsis: A mechanistic and therapeutic perspective
Published Date
Nov 20, 2020
Journal
Volume
47
Issue
1
Pages
19 - 40
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