MicroRNA-210 Regulates Dendritic Morphology and Behavioural Flexibility in Mice
Abstract
MicroRNAs are known to be critical regulators of neuronal plasticity. The highly conserved, hypoxia-regulated microRNA-210 (miR-210) has been shown to be associated with long-term memory in invertebrates and dysregulated in neurodevelopmental and neurodegenerative disease models. However, the role of miR-210 in mammalian neuronal function and cognitive behaviour remains unexplored. Here we generated Nestin-cre-driven miR-210 neuronal knockout...
Paper Details
Title
MicroRNA-210 Regulates Dendritic Morphology and Behavioural Flexibility in Mice
Published Date
Nov 9, 2020
Journal
Volume
58
Issue
4
Pages
1330 - 1344
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