Delayed urea differential enhancement CEST (dudeCEST)‐MRI with T1 correction for monitoring renal urea handling
Abstract
Purpose We demonstrate a method of delayed urea differential enhancement CEST for probing urea recycling action of the kidney using expanded multi‐pool Lorentzian fitting and apparent exchange‐dependent relaxation compensation. Methods T 1 correction of urea CEST contrast by apparent exchange‐dependent relaxation was tested in phantoms. Nine mice were scanned at 7 Tesla following intraperitoneal injection of 2M 150 μL urea, and later saline. T 1...
Paper Details
Title
Delayed urea differential enhancement CEST (dudeCEST)‐MRI with T1 correction for monitoring renal urea handling
Published Date
Nov 12, 2020
Volume
85
Issue
5
Pages
2791 - 2804
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