Nanocarriers based on vitamin E-TPGS: Design principle and molecular insights into improving the efficacy of anticancer drugs

Volume: 592, Pages: 120045 - 120045
Published: Jan 1, 2021
Abstract
α-Tocopheryl polyethylene glycol succinate (vitamin E-TPGS or TPGS) is a nonionic amphiphile synthesized by the esterification of vitamin E succinate. It has been categorized as a safe excipient by US-FDA and EMA. Like other polyethylene glycol (PEG) condensates, TPGS spontaneously forms kinetically stable core–shell micelles (diameter 12–15 nm) and exhibits interesting properties as solubilizing agent, emulsifier, dispersant and gelling agent....
Paper Details
Title
Nanocarriers based on vitamin E-TPGS: Design principle and molecular insights into improving the efficacy of anticancer drugs
Published Date
Jan 1, 2021
Volume
592
Pages
120045 - 120045
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