Total saponin extract, ginsenoside Rb1, and compound K alleviate peripheral and central neuropathic pain through estrogen receptors on rats

Volume: 35, Issue: 4, Pages: 2119 - 2132
Published: Nov 18, 2020
Abstract
In this study, we investigated whether total saponin extract (TSE), ginsenoside Rb1, and Rb1 metabolite compound K, which are isolated from red ginseng, have antinociceptive effects on peripheral and central neuropathic pain (PNP and CNP, respectively). PNP and CNP were induced by tail nerve injury (TNI) at S1 and by contusive spinal cord injury (SCI) at T9 in male Sprague–Dawley rats, respectively. Two weeks after TNI or 4 weeks after SCI,...
Paper Details
Title
Total saponin extract, ginsenoside Rb1, and compound K alleviate peripheral and central neuropathic pain through estrogen receptors on rats
Published Date
Nov 18, 2020
Volume
35
Issue
4
Pages
2119 - 2132
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