Assessment of mustard vesicant lung injury and anti‐TNF‐ α efficacy in rodents using live‐animal imaging

Nitrogen mustard (NM) causes acute lung injury, which progresses to fibrosis. This is associated with a macrophage‐dominant inflammatory response and the production of proinflammatory/profibrotic mediators, including tumor necrosis factor alpha (TNF‐α). Herein, we refined magnetic resonance imaging (MRI) and computed tomography (CT) imaging methodologies to track the progression of NM‐induced lung injury in rodents and assess the efficacy of...