Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia
Abstract
Schizophrenia (SZ) is a common and debilitating psychiatric disorder with limited effective treatment options. Although highly heritable, risk for this polygenic disorder depends on the complex interplay of hundreds of common and rare variants. Translating the growing list of genetic loci significantly associated with disease into medically actionable information remains an important challenge. Thus, establishing platforms with which to validate...
Paper Details
Title
Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia
Published Date
Jan 1, 2020
Journal
Volume
6
Issue
3-4
Pages
68 - 82
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