EUS-directed pancreatic duct drainage: Mainstream miracle or proceed with caution?

Abdominal pain is the foremost adverse event (AE) of chronic pancreatitis (CP). The mechanism of pain in CP is incompletely understood and likely multifactorial, including mechanical (intraductal pressure/obstruction), inflammatory, malabsorptive, and neurogenic/neuropathic changes in the pancreas and surrounding organs.1Anderson M.A. Akshintala V. Albers K.M. et al.Mechanism, assessment and management of pain in chronic pancreatitis:...