Mucoadhesive wafers for buccal delivery of probiotic bacteria: Mechanical properties and enumeration

The development of probiotic formulations has attracted great attention of researchers and industrial community. Their beneficial effects have been demonstrated in human health, and in buccal cavity including prevention of gingivitis, periodontitis, dental caries, oral candidiasis, and immunomodulation. The development of mucoadhesive wafers as buccal systems is important to promote intimate contact between the probiotics and oral mucosa, as...