Association of apolipoprotein C3 with insulin resistance and coronary artery calcium in patients with type 1 diabetes

Apolipoprotein C3 (APOC3) is a risk factor for incident coronary artery disease in people with type 1 diabetes (T1D). The pathways that link elevated APOC3 levels to an increased risk of incident cardiovascular disease in people with T1D are not understood.To explore potential mechanisms, we investigated the association of APOC3 with insulin resistance and coronary artery calcium (CAC).In a random subcohort of participants with T1D from Coronary...