WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer
Abstract
R-spondins control WNT signaling and RSPO1 and LGR6, two of its receptors, are uniquely expressed at high levels in high-grade serous ovarian cancer (HGSOC). The aim of this study was to assess the interrelations between the expression of the RSPOs and LGRs in HGSOC and in the ovarian surface (OSE) and fallopian tube surface epithelium (FTSE) from which HGSOC arises.Analysis of TCGA (HGSOC), CCLE (ovary), and other publicly accessed RNA-Seq data...
Paper Details
Title
WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer
Published Date
Oct 27, 2020
Journal
Volume
40
Issue
11
Pages
6017 - 6028
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History