Retinoic acid signaling and bladder cancer: Epigenetic deregulation, therapy and beyond

Volume: 148, Issue: 10, Pages: 2364 - 2374
Published: Nov 12, 2020
Abstract
Retinoic acid (RA) signaling is a crucial developmental pathway involved in urothelium development, differentiation and regeneration. Deregulation of the RA signaling is highly implicated in several cancers, including bladder cancer, underlying the need to unravel the complete regulatory aspects of the retinoids in bladder tumorigenesis. Given the fact that RA receptors are transcription factors functioning at the chromatin level and act in...
Paper Details
Title
Retinoic acid signaling and bladder cancer: Epigenetic deregulation, therapy and beyond
Published Date
Nov 12, 2020
Volume
148
Issue
10
Pages
2364 - 2374
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