Tissue-Specific Effects of Leptin on Glucose and Lipid Metabolism
Abstract
The discovery of leptin was intrinsically associated with its ability to regulate body weight. However, the effects of leptin are more far-reaching and include profound glucose-lowering and anti-lipogenic effects, independent of leptin's regulation of body weight. Regulation of glucose metabolism by leptin is mediated both centrally and via peripheral tissues and is influenced by the activation status of insulin signaling pathways. Ectopic fat...
Paper Details
Title
Tissue-Specific Effects of Leptin on Glucose and Lipid Metabolism
Published Date
Nov 5, 2020
Journal
Volume
42
Issue
1
Pages
1 - 28
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