MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma

Volume: 75, Issue: 1, Pages: 39 - 44
Published: Nov 3, 2020
Abstract
According to The Cancer Genome Atlas (TCGA), around 9% of bladder carcinomas usually show abnormalities of the murine double minute 2 (MDM2) gene, but a few studies have been investigated them. We profiled MDM2 gene amplification in a series of urothelial carcinomas (UC) considering the molecular subtypes and expression of programmed death ligand 1 (PD-L1).117 patients with muscle-invasive UC (pT2-3) without (N0) or with (N+) lymph-node...
Paper Details
Title
MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma
Published Date
Nov 3, 2020
Volume
75
Issue
1
Pages
39 - 44
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