lncRNA LINC01057 promotes mesenchymal differentiation by activating NF-κB signaling in glioblastoma
Abstract
Long non-coding RNAs (lncRNAs) have been potentially identified as new diagnostic markers, prognostic factors and therapeutic targets in cancer. The acquisition of a mesenchymal (MES) phenotype in glioblastomas (GBMs) results into therapeutic resistance and poor clinical outcomes. The correlation between lncRNAs and MES differentiation remains elusive. Here, we report that LINC01057 as a lncRNA is overexpressed in GBMs, especially in MES...
Paper Details
Title
lncRNA LINC01057 promotes mesenchymal differentiation by activating NF-κB signaling in glioblastoma
Published Date
Feb 1, 2021
Journal
Volume
498
Pages
152 - 164
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