Denosumab is not associated with risk of malignancy: systematic review and meta-analysis of randomized controlled trials
Abstract
The immunomodulatory effects of denosumab have raised concerns for risk of malignancy. This meta-analysis of 25 randomized controlled trials (21,523 patients) shows similar risk of malignancy between denosumab (60 mg every 6 months, up to 48 months) and any comparator. Post-marketing surveillance may detect rare or late-occurring drug effects. Possible increased risk of malignancy in patients treated with denosumab has been concerned due to...
Paper Details
Title
Denosumab is not associated with risk of malignancy: systematic review and meta-analysis of randomized controlled trials
Published Date
Nov 3, 2020
Journal
Volume
32
Issue
3
Pages
413 - 424
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