Comparison of the lung ventilation assessed by a full-scale airway network flow model and xenon-enhanced dual-energy CT of patients with COPD

Introduction: The medical image-based computational model technique, full-scale airway network (FAN) flow model, may be able to identify and quantify disease in patients with COPD, and replace techniques such as ventilation scanning. Objectives: We compared ventilation distribution in patients with COPD, scanned using xenon-enhanced dual-energy CT (Xe-DECT) with the computational modelling results obtained using the FAN model....