Klotho, PTSD, and advanced epigenetic age in cortical tissue
Abstract
This study examined the klotho (KL) longevity gene polymorphism rs9315202 and psychopathology, including posttraumatic stress disorder (PTSD), depression, and alcohol-use disorders, in association with advanced epigenetic age in three postmortem cortical tissue regions: dorsolateral and ventromedial prefrontal cortices and motor cortex. Using data from the VA National PTSD Brain Bank (n = 117), we found that rs9315202 interacted with PTSD to...
Paper Details
Title
Klotho, PTSD, and advanced epigenetic age in cortical tissue
Published Date
Oct 23, 2020
Journal
Volume
46
Issue
4
Pages
721 - 730
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