Automated Contouring and Planning for Hippocampal-Avoidant Whole-Brain Radiotherapy

Whole-brain radiotherapy (WBRT) remains an important treatment for over 200,000 cancer patients annually. Radiation dose to hippocampi predicts neurocognitive dysfunction. Hippocampal-avoidant WBRT (HA-WBRT) reduces neurocognitive toxicity compared to standard WBRT, but HA-WBRT contouring and planning are more complex and time-consuming than standard WBRT. We hypothesize that automated hippocampal segmentation and treatment planning can generate...