miR-1: A comprehensive review of its role in normal development and diverse disorders
Abstract
MicroRNA-1 (miR-1) is a conserved miRNA with high expression in the muscle tissues. In humans, two discrete genes, MIRN1-1 and MIRN1-2 residing on a genomic region on 18q11.2 produce a single mature miRNA which has 21 nucleotides. miR-1 has a regulatory role on a number of genes including heat shock protein 60 (HSP60), Kruppel-like factor 4 (KLF4) and Heart And Neural Crest Derivatives Expressed 2 (HAND2). miR-1 has critical roles in the...
Paper Details
Title
miR-1: A comprehensive review of its role in normal development and diverse disorders
Published Date
Oct 20, 2020
Volume
132
Pages
110903 - 110903
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