A Dosimetric Comparison Of A Novel Clitoris-Sparing Intensity Modulated Radiotherapy (IMRT) Approach vs. Standard IMRT for Treatment of Female Patients with Anal Cancer

The clitoris is the primary functional organ responsible for orgasm, sexual arousal and pleasure in females. However, current atlas-defined female sexual organs at risk (OARs) do not specifically include the clitoris and overlap only partially with the anatomic clitoral structure (∼1-2 cc). The impact of RT on the clitoris is unknown; however, since dose to the clitoris may better correlate with late sexual toxicity, avoiding the clitoris should...