Gene

Anatomy

Epidemiology

Internal medicine

Genotype

Virology

Immunology

Virus

Respiratory tract infections

Respiratory disease

Lung

Respiratory tract

Mononegavirales

Viral disease

Paramyxoviridae

Pneumovirinae

Pneumovirus

Respiratory system

Genetics

Medicine

Biology

Molecular epidemiology

Journal of Clinical Microbiology

Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection among infants and young children, resulting in annual epidemics worldwide. INFORM-RSV is a multiyear clinical study designed to describe the global molecular epidemiology of RSV in children under 5 years of age by monitoring temporal and geographical evolution of current circulating RSV strains, F protein antigenic sites, and their relationships with clinical features of RSV disease. During the pilot season (2017–2018), 410 RSV G-F gene sequences were obtained from 476 RSV-positive nasal samples collected from 8 countries (United Kingdom, Spain, The Netherlands, Finland, Japan, Brazil, South Africa, and Australia).

Global Molecular Epidemiology of Respiratory Syncytial Virus from the 2017−2018 INFORM-RSV Study