Self-amplifying RNA vaccines for infectious diseases
Abstract
Vaccinology is shifting toward synthetic RNA platforms which allow for rapid, scalable, and cell-free manufacturing of prophylactic and therapeutic vaccines. The simple development pipeline is based on in vitro transcription of antigen-encoding sequences or immunotherapies as synthetic RNA transcripts, which are then formulated for delivery. This approach may enable a quicker response to emerging disease outbreaks, as is evident from the swift...
Paper Details
Title
Self-amplifying RNA vaccines for infectious diseases
Published Date
Oct 22, 2020
Journal
Volume
28
Issue
3-4
Pages
117 - 129
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Notes
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