Molecular Imaging of Chimeric Antigen Receptor T Cells by ICOS-ImmunoPET

Volume: 27, Issue: 4, Pages: 1058 - 1068
Published: Feb 15, 2021
Abstract
Purpose: Immunomonitoring of chimeric antigen receptor (CAR) T cells relies primarily on their quantification in the peripheral blood, which inadequately quantifies their biodistribution and activation status in the tissues. Noninvasive molecular imaging of CAR T cells by PET is a promising approach with the ability to provide spatial, temporal, and functional information. Reported strategies rely on the incorporation of reporter transgenes or...
Paper Details
Title
Molecular Imaging of Chimeric Antigen Receptor T Cells by ICOS-ImmunoPET
Published Date
Feb 15, 2021
Volume
27
Issue
4
Pages
1058 - 1068
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