Cerebral MRI findings predict the risk of cognitive impairment in thrombotic thrombocytopenic purpura

Summary Thrombotic thrombocytopenic purpura (TTP) is a rare thrombomicroangiopathy caused by deficiency of ADAMTS13. Acute neurological involvement is well described, but its long‐term impact requires evaluation. One‐hundred thirty‐one patients, following an acute TTP event, with severe headache or neurological symptoms had a cerebral MRI. Fifty‐six percent had abnormal imaging, more commonly in patients with neurological symptoms than headaches...