Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases
Abstract
The extracellular matrix (ECM) is a complex network of macromolecules surrounding cells providing structural support and stability to tissues. The understanding of the ECM and the diverse roles it plays in development, homoeostasis and injury have greatly advanced in the last three decades. The ECM is crucial for maintaining tissue homoeostasis but also many pathological conditions arise from aberrant matrix remodelling during ageing. Ageing is...
Paper Details
Title
Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases
Published Date
Oct 1, 2020
Journal
Volume
134
Issue
20
Pages
2681 - 2706
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Notes
History