Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Nature64.80
Volume: 586, Issue: 7831, Pages: 763 - 768
Published: Oct 14, 2020
Abstract
Age is the dominant risk factor for most chronic human diseases, but the mechanisms through which ageing confers this risk are largely unknown1. The age-related acquisition of somatic mutations that lead to clonal expansion in regenerating haematopoietic stem cell populations has recently been associated with both haematological cancer2-4 and coronary heart disease5-this phenomenon is termed clonal haematopoiesis of indeterminate potential...
Paper Details
Title
Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Published Date
Oct 14, 2020
Journal
Volume
586
Issue
7831
Pages
763 - 768
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