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doi.org/10.1038/s41419-020-03070-z

GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma

..., Feng Tian
12
Cell Death and Disease
Volume: 11, Issue: 10
Published: Oct 15, 2020
Abstract
GATA6 acts as an oncogene or tumour suppressor in different cancers. Previously, we found that aberrant expression of GATA6 promoted metastasis in cholangiocarcinoma (CCA). However, the mechanism by which GATA6 promotes metastasis in CCA is unclear. In the present study, we aimed to investigate the role of GATA6 in CCA cell epithelial–mesenchymal transition (EMT). Our results showed that GATA6 expression was positively associated with N-cadherin...
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Paper Details
Title
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma
DOI
doi.org/10.1038/s41419-020-03070-z
Published Date
Oct 15, 2020
Journal
Cell Death and Disease
Volume
11
Issue
10
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