NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells
Volume: 21, Issue: 20, Pages: 7657 - 7657
Published: Oct 16, 2020
Abstract
Nerve Growth Factor (NGF) and its high-affinity receptor tropomyosin receptor kinase A (TRKA) increase their expression during the progression of epithelial ovarian cancer (EOC), promoting cell proliferation and angiogenesis through several oncogenic proteins, such as c-MYC and vascular endothelial growth factor (VEGF). The expression of these proteins is controlled by microRNAs (miRs), such as miR-145, whose dysregulation has been related to...
Paper Details
Title
NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells
Published Date
Oct 16, 2020
Volume
21
Issue
20
Pages
7657 - 7657
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