ACE2 as therapeutic agent.
Abstract
The angiotensin-converting enzyme 2 (ACE2) has emerged as a critical regulator of the renin-angiotensin system (RAS), which plays important roles in cardiovascular homeostasis by regulating vascular tone, fluid and electrolyte balance. ACE2 functions as a carboxymonopeptidase hydrolyzing the cleavage of a single C-terminal residue from Angiotensin-II (Ang-II), the key peptide hormone of RAS, to form Angiotensin-(1-7) (Ang-(1-7)), which binds to...
Paper Details
Title
ACE2 as therapeutic agent.
Published Date
Oct 16, 2020
Journal
Volume
134
Issue
19
Pages
2581 - 2595
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